HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 90027018, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,6-Dichloro-3-nitropyridine | HCID 85239 | — |
| Reactant | 6-Fluoro-2,3-dihydro-1H-inden-1-amine | HCID 15408127 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 90027018 | HCID 90027018 | 52% |
Reaction Steps
Dissolve 6-fluoroindan-1-ylamine (8.50 g, 56.22 mmol) in methanol (200 mL) and triethylamine (8.62 mL, 61.84 mmol). Add 2,6-dichloro-3-nitropyridine (10.85 g, 56.22 mmol) and stir under nitrogen for 14 hours. Filter the reaction mixture and wash the solids with methanol and hexanes to give the title compound as a yellow solid (9.00 g, 52%). MS (ES) m/z=308 [M+1].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062050B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-81fad4c06b2f47789f1d677e93da5c30 |
| Source note | uspto-grants-2015_06 |