Hydrochloric Acid → HCID 178428234, compound

Participants

Reaction Steps

Dissolve N2-(6-fluoroindan-1-yl)-N6-(5-methyl-2H-pyrazol-3-yl)-3-nitropyridine-2,6-diamine (0.571 g, 1.55 mmol) in methanol (10 mL). Add indium (0.890 g, 7.75 mmol) and hydrochloric acid (12N, 0.65 mL, 7.75 mmol). Stir the mixture under nitrogen for one hour. Filter the reaction mixture through Celite® 521 and wash the solids with methanol. Concentrate the filtrate in vacuo to afford crude N2-(6-fluoroindan-1-yl)-N6-(5-methyl-2H-pyrazol-3-yl)-pyridine-2,3,6-triamine dihydrochloride.

Provenance & Evidence