Hydrochloric Acid → HCID 178428191, compound

Participants

Reaction Steps

Dissolve 3-[(1R)-6-fluoro-2,3-dihydro-1H-inden-1-yl]-N-(3-methyl-1H-pyrazol-5-yl)-3H-imidazo[4,5-b]pyridin-5-amine (0.070 g, 0.201 mmol) in dichloromethane (5 mL). Add hydrogen chloride, 4 M in 1,4-dioxane (0.100 mL, 0.400 mmol). Stir the solution for 14 hours, and then concentrate to dryness in vacuo. Dissolve in methanol and concentrate to dryness in vacuo three times to give the title compound (0.067 g, 79%). MS (ES) m/z=349 [M+1].

Provenance & Evidence