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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2175064Generated: October 31, 2026

(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)boronic acid → HCID 67248446, compound

https://huagongshe.com/reaction/2175064

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)boronic acidHCID 10353857—
ReactantTert-butyl 4-(6-chloropyrazin-2-YL)piperazine-1-carboxylateHCID 18186946—
ProductHCID 67248446HCID 67248446—

Reaction Steps

The preparation is carried out analogously to FS 102 starting from 6′-chloro-2,3,5,6-tetrahydro-1,2′-bipyrazinyl-4-carboxylic acid tert-butyl ester (preparation analogous to US 2005/176722) and 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09062015B2
Source datasetuspto-grants-2015_06
ORD IDord-c7975d85b6eb4ccaada925ecbe56c3c4
Source noteuspto-grants-2015_06