HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Boc-1-(6-bromo-2-pyridyl)piperazine → 4-[6-(1,1-Dimethylindan-5-yl)pyridin-2-yl]piperazine-1-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Boc-1-(6-bromo-2-pyridyl)piperazine | HCID 16059046 | — |
| Reactant | 2-(1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 53250111 | — |
| Product | 4-[6-(1,1-Dimethylindan-5-yl)pyridin-2-yl]piperazine-1-carboxylic acid tert-butyl ester | HCID 67249093 | — |
Reaction Steps
The preparation is carried out analogously to FS 102 starting from 4-(6-bromopyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester (US 2005/176722) and 2-(1,1-dimethylindan-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062015B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-607ef9bf7e3c4607b14de649f824b90f |
| Source note | uspto-grants-2015_06 |