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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2175076Generated: October 31, 2026

Hydrochloric Acid → 2-(1-piperazinyl)-4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)Pyrimidine

https://huagongshe.com/reaction/2175076

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant4-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-pyrimidin-2-yl]piperazine-1-carboxylic acid tert-butyl esterHCID 67248680—
Product2-(1-piperazinyl)-4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)PyrimidineHCID 53250558—

Reaction Steps

The above compound is prepared analogously to FS201 starting from 4-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)pyrimidin-2-yl]piperazine-1-carboxylic acid tert-butyl ester. Product is the hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09062015B2
Source datasetuspto-grants-2015_06
ORD IDord-32010eb86fb54ab5a04bbc33a2588d6c
Source noteuspto-grants-2015_06