HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4,5,5-Tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane → HCID 67248339, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4,5,5-Tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane | HCID 11243929 | — |
| Reactant | HCID 77231001 | HCID 77231001 | — |
| Product | HCID 67248339 | HCID 67248339 | — |
Reaction Steps
The preparation is carried out analogously to FS102 starting from 106 mg (0.304 mmol) of 4-[1-(6-bromopyridin-2-yl)azepan-4-ylamino]butan-1-ol and 116 mg (0.334 mmol) of 4,4,5,5-tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane. The crude product is purified by means of RP flash chromatography on C18 silica gel. The product is in the form of the hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062015B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-644cdf29f4f341219c7f9194be8dad5e |
| Source note | uspto-grants-2015_06 |