HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4,5,5-Tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane → HCID 67249967, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4,5,5-Tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane | HCID 11243929 | — |
| Reactant | HCID 77231000 | HCID 77231000 | — |
| Product | HCID 67249967 | HCID 67249967 | — |
Reaction Steps
The preparation is carried out analogously to FS102 starting from 79 mg (0.245 mmol) of 2-[1-(6-bromopyridin-2-yl)azepan-4-ylamino]ethanol and 96 mg (0.257 mmol) of 4,4,5,5-tetramethyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3,2-dioxaborolane. The product is purified by means of preparative HPLC and converted into the hydrochloride using methanolic HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062015B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-5bf4fbf6a99b48769bc8d200746070cb |
| Source note | uspto-grants-2015_06 |