3-Bromobenzyl alcohol → (5-Bromopyridin-2-yl)methyl 4-nitrophenyl carbonate

HRID 2175241Notes

Reaction equation

HRID 2175241 reaction equation
[C:1](=O)([O:11][C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-:20])=[O:19])=[CH:14][CH:13]=1)[O:2]CC1C=CC=C(Br)C=1.BrC1C=C(CO)C=CC=1.[Br:31][C:32]1[CH:33]=[CH:34][C:35]([CH2:38][OH:39])=[N:36][CH:37]=1>>[C:1](=[O:2])([O:11][C:12]1[CH:13]=[CH:14][C:15]([N+:18]([O-:20])=[O:19])=[CH:16][CH:17]=1)[O:39][CH2:38][C:35]1[CH:34]=[CH:33][C:32]([Br:31])=[CH:37][N:36]=1

Participants

4

Reactant 3

HCID 851413-Bromobenzyl alcoholHCID 5200169(5-Bromopyridin-2-yl)methanolHCID 867125803-Bromobenzyl 4-nitrophenyl carbonate

Product 1

HCID 86712582(5-Bromopyridin-2-yl)methyl 4-nitrophenyl carbonate

Procedure

The title compound was prepared using a procedure analogous to 3-bromobenzyl 4-nitrophenyl carbonate except that (3-bromophenyl)methanol was replaced with (5-bromopyridin-2-yl)methanol. LCMS, [M+H]+=352.9.

Sources & evidence

ORD record
ord-50dfcb11d4944c1698063624d49ba8fa
Source dataset
uspto-grants-2015_06
Patent number
US09062028B2

Reaction notes

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