Propanoic acid, 2-bromo-2-methyl-, ethyl ester → Ethyl 2-(4-bromo-1H-pyrazol-1-yl)-2-methylpropanoate

HRID 2175261Notes

Reaction equation

HRID 2175261 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][N:5](CC2C=C(C=CC=2)C(OC)=O)[CH:6]=1.BrCC1C=C(C=CC=1)C(OC)=O.Br[C:31]([CH3:38])([CH3:37])[C:32]([O:34][CH2:35][CH3:36])=[O:33]>>[Br:1][C:2]1[CH:3]=[N:4][N:5]([C:31]([CH3:38])([CH3:37])[C:32]([O:34][CH2:35][CH3:36])=[O:33])[CH:6]=1

Participants

4

Reactant 3

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 517981Methyl 3-(bromomethyl)benzoateHCID 17024610methyl 3-[(4-bromo-1H-pyrazol-1-yl)methyl]benzoate

Product 1

HCID 59231678Ethyl 2-(4-bromo-1H-pyrazol-1-yl)-2-methylpropanoate

Procedure

The title compound was prepared using a procedure analogous to methyl 3-((4-bromo-1H-pyrazol-1-yl)methyl)benzoate except that methyl 3-(bromomethyl)benzoate was replaced with ethyl 2-bromo-2-methylpropanoate. LCMS, [M+H]+=261.0.

Sources & evidence

ORD record
ord-a8d7d61f66a6466bae62babb02bdc57d
Source dataset
uspto-grants-2015_06
Patent number
US09062028B2

Reaction notes

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