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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2175263Generated: October 29, 2026

3-Bromobenzyl alcohol → 2-(4-(1-(4-(2,3-Dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)-1H-pyrazol-1-yl)-2-methylpropyl 4-nitrophenyl carbonate

https://huagongshe.com/reaction/2175263

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromobenzyl alcoholHCID 85141—
Reactant4-(2,3-dimethylphenoxy)-1-(5-(1-(1-hydroxy-2-methylpropan-2-yl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-oneHCID 70983117—
Reactant3-Bromobenzyl 4-nitrophenyl carbonateHCID 86712580—
Product2-(4-(1-(4-(2,3-Dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)-1H-pyrazol-1-yl)-2-methylpropyl 4-nitrophenyl carbonateHCID 86712588—

Reaction Steps

The title compound was prepared using a procedure analogous to 3-bromobenzyl 4-nitrophenyl carbonate except that (3-bromophenyl)methanol was replaced with 4-(2,3-dimethylphenoxy)-1-(5-(1-(1-hydroxy-2-methylpropan-2-yl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-one. LCMS, [M+H]+=627.5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09062028B2
Source datasetuspto-grants-2015_06
ORD IDord-08acaf1bb3314c2daf8109629a60ceff
Source noteuspto-grants-2015_06