HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromobenzyl alcohol → 2-(4-(1-(4-(2,3-Dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)-1H-pyrazol-1-yl)-2-methylpropyl 4-nitrophenyl carbonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromobenzyl alcohol | HCID 85141 | — |
| Reactant | 4-(2,3-dimethylphenoxy)-1-(5-(1-(1-hydroxy-2-methylpropan-2-yl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-one | HCID 70983117 | — |
| Reactant | 3-Bromobenzyl 4-nitrophenyl carbonate | HCID 86712580 | — |
| Product | 2-(4-(1-(4-(2,3-Dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)-1H-pyrazol-1-yl)-2-methylpropyl 4-nitrophenyl carbonate | HCID 86712588 | — |
Reaction Steps
The title compound was prepared using a procedure analogous to 3-bromobenzyl 4-nitrophenyl carbonate except that (3-bromophenyl)methanol was replaced with 4-(2,3-dimethylphenoxy)-1-(5-(1-(1-hydroxy-2-methylpropan-2-yl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-one. LCMS, [M+H]+=627.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062028B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-08acaf1bb3314c2daf8109629a60ceff |
| Source note | uspto-grants-2015_06 |