HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dimethylphenol → 2-(3-Chloro-2-methylphenoxy)ethyl 7-bromo-1a,2-dihydro-1H-cyclopropa[c]quinoline-3(7bH)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dimethylphenol | HCID 10687 | — |
| Reactant | 3-Chloro-o-cresol | HCID 14856 | — |
| Reactant | 2-(2,3-Dimethylphenoxy)ethyl 5-bromo-3,4-dihydroquinoline-1(2H)-carboxylate | HCID 70982895 | — |
| Reactant | bromo-1a,2,3,7b-tetrahydro-1H-cyclopropa[c]quinoline | HCID 86712576 | — |
| Product | 2-(3-Chloro-2-methylphenoxy)ethyl 7-bromo-1a,2-dihydro-1H-cyclopropa[c]quinoline-3(7bH)-carboxylate | HCID 86712591 | — |
Reaction Steps
The title compound was prepared using a procedure analogous to 2-(2,3-dimethylphenoxy)ethyl 5-bromo-3,4-dihydroquinoline-1(2H)-carboxylate except that 5-bromo-1,2,3,4-tetrahydroquinoline, HCl salt was replaced with bromo-1a,2,3,7b-tetrahydro-1H-cyclopropa[c]quinoline, and 2,3-dimethylphenol was replaced with 3-chloro-2-methylphenol. LCMS, [M+Na]+=460.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062028B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-c2942e52f897424aa7c558482b179858 |
| Source note | uspto-grants-2015_06 |