HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromopyrazole → 1-(5-(1-(3-Bromobenzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-4-(2,3-dimethylphenoxy)butan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromopyrazole | HCID 16375 | — |
| Reactant | 3-Bromobenzyl bromide | HCID 69979 | — |
| Reactant | Methyl 3-(bromomethyl)benzoate | HCID 517981 | — |
| Reactant | methyl 3-[(4-bromo-1H-pyrazol-1-yl)methyl]benzoate | HCID 17024610 | — |
| Reactant | 1-(5-(1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-4-(2,3-dimethylphenoxy)butan-1-one | HCID 70982913 | — |
| Product | 1-(5-(1-(3-Bromobenzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-4-(2,3-dimethylphenoxy)butan-1-one | HCID 70983460 | — |
Reaction Steps
The title compound was prepared using a procedure analogous to methyl 3-((4-bromo-1H-pyrazol-1-yl)methyl)benzoate except that 4-bromo-1H-pyrazole was replaced with 1-(5-(1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-4-(2,3-dimethylphenoxy)butan-1-one and methyl 3-(bromomethyl)benzoate was replaced with 1-bromo-3-(bromomethyl)benzene. LCMS, [M+H]+=560.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062028B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-bbf2d46a08b14c5284992dd65e6b5e8b |
| Source note | uspto-grants-2015_06 |