HRID2175289

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12828947

Methyl 4-bromopyridine-2-carboxylate

C7H6BrNO2

HCID70982813

未命名化合物

结构：COC(=O)c1cc(-c2cccc3c2CCCN3C(=O)CCCOc2cccc(C)c2C)ccn1

HCID70982851

未命名化合物

PRODUCTS

生成物

结构：Cc1cccc(OCCCC(=O)N2CCCc3c(-c4cnn(Cc5cccc(OCCO)c5)c4)cccc32)c1C

HCID70982667

未命名化合物

PROCEDURE

实验过程

The title compound was prepared using a procedure analogous to methyl 4-(1-(4-(2,3-dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)picolinate except that methyl 4-bromopicolinate was replaced with 2-(3-((4-bromo-1H-pyrazol-1-yl)methyl)phenoxy)ethyl acetate. LCMS, [M+H]+=540.4.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c40ff2af606c4855a34d57544e5ab5de
来源数据集: uspto-grants-2015_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09062028B2
来源说明: uspto-grants-2015_06

反应 SMILES

[CH3:1][C:2]1[C:33]([CH3:34])=[CH:32][CH:31]=[CH:30][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([N:10]1[C:19]2[C:14](=[C:15](C3C=CN=C(C(OC)=O)C=3)[CH:16]=[CH:17][CH:18]=2)[CH2:13][CH2:12][CH2:11]1)=[O:9].BrC1C=CN=C(C(OC)=O)C=1.C([O:49][CH2:50][CH2:51][O:52][C:53]1[CH:58]=[CH:57][CH:56]=[C:55]([CH2:59][N:60]2[CH:64]=[C:63](Br)[CH:62]=[N:61]2)[CH:54]=1)(=O)C>>[CH3:1][C:2]1[C:33]([CH3:34])=[CH:32][CH:31]=[CH:30][C:3]=1[O:4][CH2:5][CH2:6][CH2:7][C:8]([N:10]1[C:19]2[C:14](=[C:15]([C:63]3[CH:62]=[N:61][N:60]([CH2:59][C:55]4[CH:56]=[CH:57][CH:58]=[C:53]([O:52][CH2:51][CH2:50][OH:49])[CH:54]=4)[CH:64]=3)[CH:16]=[CH:17][CH:18]=2)[CH2:13][CH2:12][CH2:11]1)=[O:9]