HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-bromopicolinate → 4-(2,3-Dimethylphenoxy)-1-(5-(1-(3-methoxybenzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-bromopicolinate | HCID 12828947 | — |
| Reactant | 4-Bromo-1-(3-methoxybenzyl)-1H-pyrazole | HCID 55137106 | — |
| Reactant | Methyl 4-(1-(4-(2,3-dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)picolinate | HCID 70982851 | — |
| Product | 4-(2,3-Dimethylphenoxy)-1-(5-(1-(3-methoxybenzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-one | HCID 70982577 | — |
Reaction Steps
The title compound was prepared using a procedure analogous to methyl 4-(1-(4-(2,3-dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)picolinate except that methyl 4-bromopicolinate was replaced with 4-bromo-1-(3-methoxybenzyl)-1H-pyrazole. LCMS, [M+H]+=510.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062028B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-17ec68a3ec1e43099f6fc6c0d1a5fddc |
| Source note | uspto-grants-2015_06 |