HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-1-(3-methoxybenzyl)-1H-pyrazole → 4-(2,3-Dimethylphenoxy)-1-(5-(1-(3-hydroxybenzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-1-(3-methoxybenzyl)-1H-pyrazole | HCID 55137106 | — |
| Reactant | 4-(2,3-Dimethylphenoxy)-1-(5-(1-(3-methoxybenzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-one | HCID 70982577 | — |
| Reactant | 3-((4-Bromo-1H-pyrazol-1-yl)methyl)phenol | HCID 70982914 | — |
| Product | 4-(2,3-Dimethylphenoxy)-1-(5-(1-(3-hydroxybenzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-one | HCID 70983580 | — |
Reaction Steps
The title compound was prepared using a procedure analogous to 3-((4-bromo-1H-pyrazol-1-yl)methyl)phenol except that 4-bromo-1-(3-methoxybenzyl)-1H-pyrazole was replaced with 4-(2,3-dimethylphenoxy)-1-(5-(1-(3-methoxybenzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)butan-1-one. LCMS, [M+H]+=496.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062028B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-0c514956084f44cfbf4f261e73db21bd |
| Source note | uspto-grants-2015_06 |