HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-1-propanol → 1-(5-(1-(3-(3-Bromopropoxy)benzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-4-(2,3-dimethylphenoxy)butan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-1-propanol | HCID 12308 | — |
| Reactant | tert-butyl N-({[(tert-butoxy)carbonyl]amino}methanimidoyl)carbamate | HCID 135638421 | — |
| Reactant | HCID 178425706 | HCID 178425706 | — |
| Product | 1-(5-(1-(3-(3-Bromopropoxy)benzyl)-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-4-(2,3-dimethylphenoxy)butan-1-one | HCID 86712600 | — |
Reaction Steps
The title compound was prepared using a procedure analogous to tert-butyl (tert-butoxycarbonylamino)(2-(3-((4-(1-(4-(2,3-dimethylphenoxy)butanoyl)-1,2,3,4-tetrahydroquinolin-5-yl)-1H-pyrazol-1-yl)methyl)phenoxy)ethylamino)-methylenecarbamate except that 1,3-bis(tert-butoxycarbonyl)-guanidine was replaced with 3-bromopropan-1-ol. LCMS, [M+H]+=616.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062028B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-b29dc465d2874b879e6b749591e93b5c |
| Source note | uspto-grants-2015_06 |