HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2,3-Dimethylphenoxy)butanoic acid → Methyl 1-(5-bromo-1,2,3,4-tetrahydroquinoline-1-carbonyl)cyclopropanecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2,3-Dimethylphenoxy)butanoic acid | HCID 1622524 | — |
| Reactant | 1-(Methoxycarbonyl)cyclopropane-1-carboxylic acid | HCID 13861823 | — |
| Reactant | 1-(5-Bromo-3,4-dihydroquinolin-1(2H)-yl)-4-(2,3-dimethylphenoxy)butan-1-one | HCID 70981796 | — |
| Product | Methyl 1-(5-bromo-1,2,3,4-tetrahydroquinoline-1-carbonyl)cyclopropanecarboxylate | HCID 70982909 | — |
Reaction Steps
The title compound was prepared using a procedure analogous to 1-(5-bromo-3,4-dihydroquinolin-1(2H)-yl)-4-(2,3-dimethylphenoxy)butan-1-one except that 4-(2,3-dimethylphenoxy)butanoic acid was replaced with 1-(methoxycarbonyl)cyclopropanecarboxylic acid. LCMS, [M+H]+=338.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062028B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-60757d9a2fcd448887272244060892ef |
| Source note | uspto-grants-2015_06 |