Hydrochloric Acid → HCID 58565372, compound

Participants

Reaction Steps

Hydrogen chloride (4.0 M) in 1,4-dioxane (1.2 mL, 4.8 mmol) was added to a solution of tert-butyl {1-[3-bromo-1-(3-fluorophenyl)-1H-indol-2-yl]ethyl}carbamate (0.15 g, 0.35 mmol) in 1,4-dioxane (2.0 mL) The reaction was stirred at room temperature for 2 hours. The mixture was diluted with EtOAc, washed with saturated NaHCO3 solution, dried over MgSO4 and concentrated to give the crude product (0.12 g). LCMS calculated for C16H12BrFN (M-NH2)+: m/z=316.0. Found: 316.0.

Provenance & Evidence