Trifluoroacetic acid → HCID 58565378, compound

Participants

Reaction Steps

To a mixture of tert-butyl {1-[3-fluoro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate (16 mg, 0.043 mmol) in methylene chloride (1 mL) was added trifluoroacetic acid (0.033 mL, 0.43 mmol). The reaction was stirred at room temperature for 1 hour. The reaction was quenched with saturated NaHCO3 solution and then extracted with dichloromethane. The combined organic layers were dried over MgSO4 and concentrated to give the desired amine (11 mg, 94%). LCMS calculated for C15H14F2N3(M+H)+: m/z=274.1. Found: 274.1.

Provenance & Evidence