HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,6-Dichloro-2-methylpyrimidine → 6-chloro-N-((2,4-dimethylthiazol-5-yl)methyl)-2-methylpyrimidin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,6-Dichloro-2-methylpyrimidine | HCID 234997 | — |
| Reactant | (Dimethyl-1,3-thiazol-5-yl)methanamine | HCID 25219195 | — |
| Product | 6-chloro-N-((2,4-dimethylthiazol-5-yl)methyl)-2-methylpyrimidin-4-amine | HCID 86729567 | — |
Reaction Steps
The title compound was prepared from 4,6-dichloro-2-methylpyrimidine and (2,4-dimethylthiazol-5-yl)methanamine according to the protocol outlined in Example 1, to afford 3A-1 as a solid. LRMS (ES) (M+H)+: observed=269.1, calculated=269.7.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062059B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-ccba840ce6df437aa8be4a2dc119943d |
| Source note | uspto-grants-2015_06 |