4,6-Dichloro-2-methylpyrimidine → HCID 86729568, compound

HRID 2175407Notes

Reaction equation

HRID 2175407 reaction equation
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[C:4]([CH3:9])[N:3]=1.[CH3:10][C:11]1[S:15][C:14]([CH2:16][NH2:17])=[N:13][N:12]=1>>[Cl:8][C:6]1[N:5]=[C:4]([CH3:9])[N:3]=[C:2]([NH:17][CH2:16][C:14]2[S:15][C:11]([CH3:10])=[N:12][N:13]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 2349974,6-Dichloro-2-methylpyrimidineHCID 11615232(5-methyl-1,3,4-thiadiazol-2-yl)methanamine

Product 1

HCID 86729568HCID 86729568, compound

Procedure

The title compound was prepared from 4,6-dichloro-2-methylpyrimidine and (5-methyl-1,3,4-thiadiazol-2-yl)methanamine according to the protocol outlined in Example 1, to afford 8-1 as a solid. LRMS (ES) (M+H)+: observed=256.1, calculated=256.7.

Sources & evidence

ORD record
ord-0f2354b713b342d6b90a4edb7ad07719
Source dataset
uspto-grants-2015_06
Patent number
US09062059B2

Reaction notes

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