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HRID2175860

反应详情

EQUATION

反应方程式

HRID 2175860 的结构方程式

REACTANTS

反应物

2
结构：Cc1c([C@@H]2CO2)ccc2c1COC2=O
HCID59568646

4-Methyl-5-[(2R)-oxiran-2-yl]-2-benzofuran-1(3H)-one

C11H10O3

结构：Cc1c(C(O)CN2CCN(C(=O)OC(C)(C)C)C[C@H]2CO)ccc2c1COC2=O
HCID71270662

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c([C@@H](O)CN2CCN(C(=O)OC(C)(C)C)C[C@H]2CO)ccc2c1COC2=O
HCID86727078

未命名化合物

PROCEDURE

实验过程

(S)-tert-Butyl 4-((R)-2-hydroxy-2-(4-methyl-1-oxo-1,3-dihydroisobenzofuran-5-yl)ethyl)-3-(hydroxymethyl)piperazine-1-carboxylate was prepared starting from 4-methyl-5-[(2R)-oxiran-2-yl]-2-benzofuran-1(3H)-one in an analogous fashion to that described above for the synthesis of (S)-tert-butyl 4-(2-hydroxy-2-(4-methyl-1-oxo-1,3-dihydroisobenzofuran-5-yl)ethyl)-3-(hydroxymethyl)piperazine-1-carboxylate.