HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoro-6-nitroanisole → 3-Fluoro-2-methoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoro-6-nitroanisole | HCID 598606 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Fluoro-2-methoxyaniline | HCID 581109 | — |
Reaction Steps
A mixture of 1-fluoro-2-methoxy-3-nitrobenzene (25.0 g, 146 mmol) and Pd/C (10%, 7.5 g) in 500 mL of MeOH was stirred at room temperature under 55 psi of H2 for 4 hours before filtration. The filtrate was concentrated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062070B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-83429c9e9074418a9b6d34fd14195ce7 |
| Source note | uspto-grants-2015_06 |