HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Difluoro-3-nitrobenzoyl chloride → (3-Amino-2,6-difluoro-phenyl)-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Difluoro-3-nitrobenzoyl chloride | HCID 2781756 | — |
| Reactant | 5-methyl-1H-pyrrolo[2,3-b]pyridine | HCID 20597429 | — |
| Product | (3-Amino-2,6-difluoro-phenyl)-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone | HCID 58086440 | — |
Reaction Steps
(3-Amino-2,6-difluoro-phenyl)-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone 17 was prepared in two steps from 2,6-difluoro-3-nitro-benzoyl chloride 14 and 5-methyl-1H-pyrrolo[2,3-b]pyridine 15 as shown in Scheme 1a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198273B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-1e7d9015c8dc432380832ceab9661323 |
| Source note | uspto-grants-2012_06 |