HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86727105, compound → HCID 86727106, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86727105 | HCID 86727105 | — |
| Solvent | Nitrobenzene | HCID 7416 | — |
| Product | HCID 86727106 | HCID 86727106 | — |
Reaction Steps
A solution of tert-butyl ethyl but-3-yn-1-yl(5-nitropyrimidin-2-yl)propanedioate (10.2 g, 28.1 mmol) in 100 mL of nitrobenzene was heated to 150° C. for 4 hours. Nitrobenzene was removed by vacuum and the residue was purified by column chromatography (Petroleum ether:EtOAc=10:1) to afford the title compound; MS m/z 337 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09062070B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-a71fab43b42c4a4a9f51776ab84f36f8 |
| Source note | uspto-grants-2015_06 |