HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2175935Generated: October 25, 2026
Ethanol → 6-methyl-3-(2H-1,2,3-triazol-2-yl)picolinic acid
https://huagongshe.com/reaction/2175935
Participants
| Role | Name | HCID | Charge |
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| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 6-Methyl-3-(2H-1,2,3-triazol-2-yl)picolinonitrile | HCID 68281582 | — |
| Product | 6-methyl-3-(2H-1,2,3-triazol-2-yl)picolinic acid | HCID 59363733 | — |
Reaction Steps
To a solution of the title compound of Step A (730 mg, 4 mmol) in EtOH (10 mL) was added 4 N NaOH (1 mL, 4 mmol). The mixture was heated at 100° C. for 24 h. The reaction mixture was concentrated in vacuo to a white solid which was used without further purification in subsequent steps.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09062078B2 |
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| Source dataset | uspto-grants-2015_06 |
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| ORD ID | ord-eb837fd85db84ac6b61acf6793cc84d7 |
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| Source note | uspto-grants-2015_06 |
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