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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2175935Generated: October 25, 2026

Ethanol → 6-methyl-3-(2H-1,2,3-triazol-2-yl)picolinic acid

https://huagongshe.com/reaction/2175935

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantSodium HydroxideHCID 14798—
Reactant6-Methyl-3-(2H-1,2,3-triazol-2-yl)picolinonitrileHCID 68281582—
Product6-methyl-3-(2H-1,2,3-triazol-2-yl)picolinic acidHCID 59363733—

Reaction Conditions

Temperature100 °C

Reaction Steps

To a solution of the title compound of Step A (730 mg, 4 mmol) in EtOH (10 mL) was added 4 N NaOH (1 mL, 4 mmol). The mixture was heated at 100° C. for 24 h. The reaction mixture was concentrated in vacuo to a white solid which was used without further purification in subsequent steps.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09062078B2
Source datasetuspto-grants-2015_06
ORD IDord-eb837fd85db84ac6b61acf6793cc84d7
Source noteuspto-grants-2015_06