HCID 90412485, compound → HCID 90411993, compound

HRID 2175962Notes

Reaction equation

HRID 2175962 reaction equation
N1C=CC=C(OCC2CC3N(C(OC(C)(C)C)=O)C2CC3)N=1.[CH3:23][N:24]1[C:28]([O:29][CH2:30][CH:31]2[CH2:36][CH:35]3[N:37](C(OC(C)(C)C)=O)[CH:32]2[CH2:33][CH2:34]3)=[CH:27][CH:26]=[N:25]1>>[CH3:23][N:24]1[C:28]([O:29][CH2:30][CH:31]2[CH2:36][CH:35]3[NH:37][CH:32]2[CH2:33][CH2:34]3)=[CH:27][CH:26]=[N:25]1

Participants

3

Reactant 2

HCID 90412485HCID 90412485, compoundHCID 90412875HCID 90412875, compound

Product 1

HCID 90411993HCID 90411993, compound

Procedure

Prepared analogous to Example 53 Step B substituting (±)-tert-butyl 2-((pyridazin-3-yloxy)methyl)-7-azabicyclo[2.2.1]heptane-7-carboxylate the title compound of Step A. MS (ESI) mass calcd. for C11H17N3O, 207.1; m/z found 208.0 [M+H]+.

Workup

  1. customPrepared analogous to Example 53 Step B

Sources & evidence

ORD record
ord-634b9315fc26466a908ea3e95fcb5d78
Source dataset
uspto-grants-2015_06
Patent number
US09062078B2

Reaction notes

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