HCID 90411387, compound → HCID 90411938, compound

HRID 2175978Notes

Reaction equation

HRID 2175978 reaction equation
C(OC(N1C2CCC1C(NC1C=CC=C(C(F)(F)F)N=1)C2)=O)(C)(C)C.[Cl:26][C:27]1[CH:28]=[CH:29][C:30]2[O:34][C:33]([NH:35][CH:36]3[CH2:41][CH:40]4[N:42](C(OC(C)(C)C)=O)[CH:37]3[CH2:38][CH2:39]4)=[N:32][C:31]=2[CH:50]=1>>[ClH:26].[CH:37]12[NH:42][CH:40]([CH2:39][CH2:38]1)[CH2:41][CH:36]2[NH:35][C:33]1[O:34][C:30]2[CH:29]=[CH:28][C:27]([Cl:26])=[CH:50][C:31]=2[N:32]=1

Participants

3

Reactant 2

HCID 90411387HCID 90411387, compoundHCID 90411878HCID 90411878, compound

Product 1

HCID 90411938HCID 90411938, compound

Procedure

Prepared analogous to Example 209 substituting (±)-tert-butyl-2-((6-(trifluoromethyl)pyridin-2-yl)amino)-7-azabicyclo[2.2.1]heptane-7-carboxylate with the title compound of step A. MS (ESI) mass calcd. for C13H14ClN3O, 263.1; m/z found 264.0 [M+H]+.

Sources & evidence

ORD record
ord-fac7d0e1e85a4fea9f603d25a454fc06
Source dataset
uspto-grants-2015_06
Patent number
US09062078B2

Reaction notes

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