(2-Methoxyethoxy)acetic acid → HCID 90370248, compound

HRID 2176007Notes

Reaction equation

HRID 2176007 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][C:7]([OH:9])=O.[CH3:10][NH:11][CH2:12][CH2:13][CH2:14][OH:15]>>[OH:15][CH2:14][CH2:13][CH2:12][N:11]([CH3:10])[C:7](=[O:9])[CH2:6][O:5][CH2:4][CH2:3][O:2][CH3:1]

Participants

3

Reactant 2

HCID 27642(2-Methoxyethoxy)acetic acidHCID 101489863-(Methylamino)-1-propanol

Product 1

HCID 90370248HCID 90370248, compound

Procedure

By using 1.4 mL of (2-methoxyethoxy)acetic acid and 1.0 g of 3-(methylamino)propan-1-ol as starting materials, the reaction similar to Preparation Example 16 was performed, thereby obtaining 2.19 g of N-(3-hydroxypropyl)-2-(2-methoxyethoxy)-N-methylacetamide.

Workup

  1. customthe reaction
  2. customsimilar to Preparation Example 16

Sources & evidence

ORD record
ord-98ca69756a2e414f9df8122833c55746
Source dataset
uspto-grants-2015_06
Patent number
US09062032B2

Reaction notes

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