Trifluoroacetic acid → HCID 90370243, compound

Participants

Reaction Steps

By using 1.71 g of tert-butyl 3-(hydroxymethyl)-4-[3-({3-[(4-{2-[4-(methoxycarbonyl)phenyl]ethyl}phenyl)carbamoyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl}carbamoyl)benzyl]piperazine-1-carboxylate and 17 mL of TFA, a reaction was performed under the conditions similar to Preparation Example 12, thereby obtaining 1.38 g of methyl 4-(2-{4-[({2-[(3-{[2-(hydroxymethyl)piperazin-1-yl]methyl}benzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophen-3-yl}carbonyl)amino]phenyl}ethyl)benzoate.

Provenance & Evidence