HCID 22080627, compound → HCID 90370099, compound

Participants

Reaction Steps

By using 23 mg of methyl 4-[2-(4-{[(2-{[3-(chloromethyl)benzoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)carbonyl]amino}phenyl)ethyl]benzoate and 19 mg of methyl[(1-ethylpropyl)amino]acetate as starting materials, alkylation was performed under the conditions similar to Preparation Example 30, and then hydrolysis was performed under the conditions similar to Example 6, thereby obtaining 6.7 mg of 4-(2-{4-[({2-[(3-{[(carboxymethyl)(pentan-3-yl)amino]methyl}benzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophen-3-yl}carbonyl)amino]phenyl}ethyl)benzoic acid.

Provenance & Evidence