1-(2-Bromoethyl)-3-fluorobenzene → HCID 86640686, compound

HRID 2176096Notes

Reaction equation

HRID 2176096 reaction equation
[C:1]1([C:7]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[N:8][NH:9][C:10]2[CH:15]=[CH:14][C:13]([CH3:16])=[CH:12][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:23][C:24]1[CH:25]=[C:26]([CH:30]=[CH:31][CH:32]=1)[CH2:27][CH2:28]Br>>[C:17]1([C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[N:8][N:9]([CH2:28][CH2:27][C:26]2[CH:30]=[CH:31][CH:32]=[C:24]([F:23])[CH:25]=2)[C:10]2[CH:11]=[CH:12][C:13]([CH3:16])=[CH:14][CH:15]=2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 5731291-(2-Bromoethyl)-3-fluorobenzeneHCID 6426133HCID 6426133, compound

Product 1

HCID 86640686HCID 86640686, compound

Procedure

General procedure B was used to convert 1-(diphenylmethylene)-2-p-tolylhydrazine (200 mg, 0.69 mmol; Example 36A) and 3-fluorophenethylbromide (1.38 g, 6.7 mmol; Aldrich) to the title compound: MS (DCI/NH3) m/z 409 (M+H)+.

Sources & evidence

ORD record
ord-47e8fa3bb7254b7aaff0725aebc34cc2
Source dataset
uspto-grants-2015_06
Patent number
US09063126B2

Reaction notes

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