Sodium Bicarbonate → HCID 57696848, compound

Participants

Reaction Steps

A solution of 7 (1.3 g, 2.6 mmol) in dry THF (6 mL) was treated with a nBu4NF (1.6 g, 5 mmol). After 1 h, a saturated solution of NaHCO3 (30 mL) was added. The mixture was extracted with EtOAc (3×30 mL). The organic phase was dried, filtered and concentrated in vacuum. The residue was purified by flash chromatography (SiO2, 3×10 cm, 25% Et2O-hexanes) to give 8 (0.86 g, 86%, white solid, mp: 95° C.), Elementary analysis: C=68.12%, H=11.18%

Provenance & Evidence