Cornforth reagent → HCID 57696852, compound

Participants

Reaction Steps

A solution of 13a (123 mg, 0.4 mmol) in dry CH2Cl2 (10 mL) was treated with PDC (pyridinium dichromate, 0.6 g, 1.6 mmol). The mixture was stirred at room temperature for 20 h. The mixture was filtered and concentrated in vacuum. The residue was purified by flash chromatography (SiO2, 3×5.5 cm, 20% EtOAc-hexanes) to give 1S (120 mg, 98%, white solid, mp: 87° C.). Elemental analysis C=73.80%, H=10.51%.

Provenance & Evidence