Methyl iodide → HCID 15354988, compound

HRID 2176379Notes

Reaction equation

HRID 2176379 reaction equation
[CH:1]([O:3][CH2:4][CH2:5][O:6][CH2:7][CH2:8][O:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][O:18][CH2:19][CH2:20][O:21][CH2:22][CH2:23][OH:24])=[CH2:2].[OH-].[Na+].[CH3:27]I>>[CH:1]([O:3][CH2:4][CH2:5][O:6][CH2:7][CH2:8][O:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][O:18][CH2:19][CH2:20][O:21][CH2:22][CH2:23][O:24][CH3:27])=[CH2:2]

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 14798Sodium HydroxideHCID 21097575HCID 21097575, compound

Product 1

HCID 15354988HCID 15354988, compound

Conditions

Temperature
40 °C

Procedure

A 1-L flask equipped with a stirrer, a dropping funnel, a thermometer, a condenser tube, and a nitrogen gas inlet was charged with 50 parts of heptaethylene glycol vinyl ether and 11 parts of sodium hydroxide. The flask was heated to 40° C. with stirring under a nitrogen atmosphere, and then 40 parts of methyl iodide was slowly dropped while the internal temperature was maintained at 40° C. or lower. After completion of the dropping, the mixture was aged for five hours, and distilled under reduced pressure so that unreacted methyl iodide was removed. In order to further remove sodium hydroxide in excess and water and sodium iodide generated after the reaction, adsorption treatment was performed using an adsorbent, and thereby heptaethylene glycol methyl vinyl ether was obtained.

Workup

  1. customA 1-L flask equipped with a stirrer, a dropping funnel
  2. temperaturewas maintained at 40° C.
  3. distillationdistilled under reduced pressure so that unreacted methyl iodide
  4. customwas removed
  5. customIn order to further remove sodium hydroxide in excess and water and sodium iodide
  6. customafter the reaction, adsorption treatment

Sources & evidence

ORD record
ord-290c2a0793b94e209dccc804247d0a0c
Source dataset
uspto-grants-2015_06
Patent number
US09065150B2

Reaction notes

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