3-(Trifluoromethyl)phenyl isocyanate → HCID 86620418, compound

HRID 217655Notes

Reaction equation

HRID 217655 reaction equation
C1(P(=[N:20][C:21]2[C:22](/[CH:27]=[CH:28]/[C:29]([O:31][C:32]([CH3:35])([CH3:34])[CH3:33])=[O:30])=[N:23][CH:24]=[CH:25][CH:26]=2)(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[F:36][C:37]([F:48])([F:47])[C:38]1[CH:39]=[C:40]([N:44]=[C:45]=O)[CH:41]=[CH:42][CH:43]=1>>[F:36][C:37]([F:47])([F:48])[C:38]1[CH:39]=[C:40]([N:44]=[C:45]=[N:20][C:21]2[C:22](/[CH:27]=[CH:28]/[C:29]([O:31][C:32]([CH3:33])([CH3:34])[CH3:35])=[O:30])=[N:23][CH:24]=[CH:25][CH:26]=2)[CH:41]=[CH:42][CH:43]=1

Participants

3

Reactant 2

HCID 94833-(Trifluoromethyl)phenyl isocyanateHCID 59168071HCID 59168071, compound

Product 1

HCID 86620418HCID 86620418, compound

Procedure

65 mg (0.14 mmol) of iminophosphorane from Example 11A are reacted by general procedure [B] with 27 mg (0.14 mmol) of 3-trifluoromethylphenyl isocyanate, and the crude product is reacted further without purification.

Sources & evidence

ORD record
ord-9572f7ef1c6542c49454b097c717203a
Source dataset
uspto-grants-2012_06
Patent number
US08198282B2

Reaction notes

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