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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2176611Generated: November 2, 2026

1-(3-Fluoro-5-(3-methylisoxazol-5-yl)pyridin-2-yl)hydrazine → 4-((8-Fluoro-6-(3-methylisoxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methoxy)quinolin-7-ol

https://huagongshe.com/reaction/2176611

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Fluoro-5-(3-methylisoxazol-5-yl)pyridin-2-yl)hydrazineHCID 58015486—
Reactant2-(7-hydroxyquinolin-4-yloxy)acetic Acid HydrobromideHCID 136330124—
Product4-((8-Fluoro-6-(3-methylisoxazol-5-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)methoxy)quinolin-7-olHCID 135987471—

Reaction Steps

The material was prepared using general method A (with 2-(7-hydroxyquinolin-4-yloxy)acetic acid hydrobromide and 1-(3-fluoro-5-(3-methylisoxazol-5-yl)pyridin-2-yl)hydrazine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09066954B2
Source datasetuspto-grants-2015_06
ORD IDord-f3df52a2683f4c43801614bb7e91d1a4
Source noteuspto-grants-2015_06