5-Chloro-3-fluoro-2-hydrazinylpyridine → HCID 57691229, compound

HRID 2176644Notes

Reaction equation

HRID 2176644 reaction equation
[F:1][C:2]([F:18])([C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[N:12]=[CH:11][C:10]([O:16][CH3:17])=[CH:9]2)[C:3]([OH:5])=O.[Cl:19][C:20]1[CH:21]=[C:22]([F:28])[C:23]([NH:26][NH2:27])=[N:24][CH:25]=1>>[Cl:19][C:20]1[CH:21]=[C:22]([F:28])[C:23]([NH:26][NH:27][C:3](=[O:5])[C:2]([F:1])([F:18])[C:6]2[CH:7]=[C:8]3[C:13](=[CH:14][CH:15]=2)[N:12]=[CH:11][C:10]([O:16][CH3:17])=[CH:9]3)=[N:24][CH:25]=1

Participants

3

Reactant 2

HCID 226196745-Chloro-3-fluoro-2-hydrazinylpyridineHCID 576912392,2-Difluoro-2-(3-methoxyquinolin-6-yl)acetic acid

Product 1

HCID 57691229HCID 57691229, compound

Procedure

This compound was assembled from 2,2-difluoro-2-(3-methoxyquinolin-6-yl)acetic acid and 1-(5-chloro-3-fluoropyridin-2-yl)hydrazine according to General Method I. LRMS (ESI) ml: calcd for C17H13ClF3N4O2S (M+H) 397.1. found 397.2.

Sources & evidence

ORD record
ord-f955e12eb5634b56aa7679db83ea3ec2
Source dataset
uspto-grants-2015_06
Patent number
US09066954B2

Reaction notes

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