4-Bromo-1-phenyl-1H-pyrazole → 1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

HRID 2176673Notes

Reaction equation

HRID 2176673 reaction equation
[CH2:1]([N:3]1[CH:7]=[C:6]([B:8]2[O:12][C:11]([CH3:14])([CH3:13])[C:10]([CH3:16])([CH3:15])[O:9]2)[CH:5]=[N:4]1)[CH3:2].BrC1C=NN([C:23]2[CH:28]=CC=[CH:25][CH:24]=2)C=1>>[C:1]1([N:3]2[CH:7]=[C:6]([B:8]3[O:12][C:11]([CH3:14])([CH3:13])[C:10]([CH3:15])([CH3:16])[O:9]3)[CH:5]=[N:4]2)[CH:25]=[CH:24][CH:23]=[CH:28][CH:2]=1

Participants

3

Reactant 2

HCID 7868114-Bromo-1-phenyl-1H-pyrazoleHCID 113790451-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester

Product 1

HCID 569657711-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Procedure

The title compound was prepared in the same manner as 1-ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole starting with 4-bromo-1-phenyl-1H-pyrazole.

Sources & evidence

ORD record
ord-46be1397fd714352b54b43755e488394
Source dataset
uspto-grants-2015_06
Patent number
US09066954B2

Reaction notes

Loading…