HRID2176779

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID292050

4-Hydroxy-4-(methylimino)butanoic acid

C5H9NO3

结构：COC(=O)N1CC[C@H]2[C@@H]1CCC[C@]2(O)C#Cc1cccc(C)c1

HCID68276168

Methyl (3aS,4R,7aS)-octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylate

C19H23NO3

PRODUCTS

生成物

结构：CNC(=O)CCC(=O)O[C@@]1(C#Cc2cccc(C)c2)CCC[C@@H]2[C@H]1CCN2C(=O)OC

HCID86702180

未命名化合物

PROCEDURE

实验过程

Synthesis in analogy to the General Method 1 starting from (3aS,4R,7aS)-4-hydroxy-4-m-tolylethynyl-octahydro-indole-1-carboxylic acid methyl ester and N-methylsuccinamic acid to yield (3aR,4S,7aR)-methyl 4-(4-(methylamino)-4-oxobutanoyloxy)-4-(m-tolylethynyl)octahydro-1H-indole-1-carboxylate. MS [M+H]=427; RT=1.06 min; UPLC Method I