Oxygen → 1-(3-tert-Butyl-5-methoxymethylphenyl)ethanone

HRID 217724Notes

Reaction equation

[C:1]([C:5]1[CH:6]=[C:7]([CH:12]=[C:13]([CH2:15][OH:16])[CH:14]=1)[C:8]([O:10][CH3:11])=O)([CH3:4])([CH3:3])[CH3:2].[CH3:17]I.O=O>>[C:1]([C:5]1[CH:14]=[C:13]([C:15](=[O:16])[CH3:17])[CH:12]=[C:7]([CH2:8][O:10][CH3:11])[CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 3

HCID 977Oxygen

HCID 6328Methyl iodide

HCID 12144659Methyl 3-tert-butyl-5-(hydroxymethyl)benzoate

Product 1

HCID 581369281-(3-tert-Butyl-5-methoxymethylphenyl)ethanone

Procedure

Methyl 3-tert-butyl-5-hydroxymethylbenzoate was reacted with methyl iodide analogously to O5.043, and converted to the title compound analogously to the sequence O4.008 to O2.008. 1.54 g were obtained.

Sources & evidence

ORD record: ord-89a58e02fb4741ed82148764e4a87a3a
Source dataset: uspto-grants-2012_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08198272B2

Reaction notes

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