Ethyl 3-(4-hydroxy-2,3-dimethylphenyl)propanoate → HCID 90418231, compound

HRID 2177262Notes

Reaction equation

HRID 2177262 reaction equation
CS([O:5][CH2:6][C:7]1[C:8]([Cl:20])=[N:9][S:10][C:11]=1[C:12]1[CH:17]=[CH:16][C:15]([CH2:18][CH3:19])=[CH:14][CH:13]=1)(=O)=O.O[C:22]1[CH:27]=[CH:26][C:25]([CH2:28][CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31])=[C:24]([CH3:35])[C:23]=1[CH3:36]>>[Cl:20][C:8]1[C:7]([CH2:6][O:5][C:22]2[CH:27]=[CH:26][C:25]([CH2:28][CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31])=[C:24]([CH3:35])[C:23]=2[CH3:36])=[C:11]([C:12]2[CH:17]=[CH:16][C:15]([CH2:18][CH3:19])=[CH:14][CH:13]=2)[S:10][N:9]=1

Participants

3

Reactant 2

HCID 58566491Ethyl 3-(4-hydroxy-2,3-dimethylphenyl)propanoateHCID 90418885HCID 90418885, compound

Product 1

HCID 90418231HCID 90418231, compound

Procedure

The title compound was prepared according to the procedure described in Example 127 following Step 6 by coupling [3-chloro-5-(4-ethylphenyl)-1,2-thiazol-4-yl]methyl methanesulfonate and ethyl 3-(4-hydroxy-2,3-dimethylphenyl)propanoate to afford the desired product as a yellow oil.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-5787052aec074712808c3228961a30b4
Source dataset
uspto-grants-2015_06
Patent number
US09067898B1

Reaction notes

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