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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 21773Generated: October 28, 2026

L-Proline → 1-L-Alanyl-D-proline

https://huagongshe.com/reaction/21773

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-ProlineHCID 145742—
Reactant(R)-1-((R)-2-Aminopropanoyl)pyrrolidine-2-carboxylic acidHCID 6993389—
Product1-L-Alanyl-D-prolineHCID 108985—

Reaction Steps

By substituting D-proline for L-proline in the above example, a 70% diastereomeric excess mixture of D-alanyl-D-proline and L-alanyl-D-proline was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05424454
Source datasetuspto-grants-1995_06
ORD IDord-7c5c474dbd28494d887887522b80854c
Source noteuspto-grants-1995_06