HCID 59438430, compound → HCID 59438519, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 55 mg (0.218 mmol) rac-3-fluoro-1-methyl-5-nitro-5-phenyl-piperidin-2-one in 1.5 ml THF at 0° C. was added 100 ul Raney Nickel (50% in water). The mixture was stirred under a hydrogen atmosphere at 0° C. for 2 hours. The mixture was filtered and the catalyst was washed with THF. The filtrate was concentrated in vacuo to provide 48 mg (99%) of the title compound as a light yellow solid. MS (m/e): 223.3 (M+H).

Provenance & Evidence