Rac-5-cyclohexyl-1-methyl-5-nitro-piperidin-2-one → HCID 59438513, compound

Participants

Reaction Steps

To a solution of 500 mg (2.08 mmol) rac-5-cyclohexyl-1-methyl-5-nitro-piperidin-2-one in 5 ml methanol were added 500 mg wet Raney Nickel and the mixture stirred under a hydrogen atmosphere at normal pressure and ambient temperature for 22 hours. Then the reaction mixture was filtered through a Dicalite pad, the precipitate washed with methanol and the filtrate evaporated: 452 mg title compound were obtained as colourless oil which was used without purification for the next step.

Provenance & Evidence