Lawesson's reagent → HCID 59438526, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 125 mg (0.531 mmol) rac-1-Methyl-3-nitro-2,3,4,5-tetrahydro-1H-[3,4]bipyridinyl-6-one in 2.5 ml toluene were added 240 mg (0.584 mmol) Lawesson reagent. The suspension was heated in a 80° C. oil bath for 30 minutes. The mixture was concentrated in vacuo. The crude oil was purified on silica gel (Eluent: Heptane/ethyl acetate 0 to 100%) to provide 105 mg (79%) of the title compound as a light yellow solid. MS (m/e): 252.1 (M+H).

Provenance & Evidence