HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-Isopropyl-4-trifluoromethyl-benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 2-iodo-4-(trifluoromethyl)benzoate | HCID 59438424 | — |
| Reactant | HCID 178461827 | HCID 178461827 | — |
| Product | 2-Isopropyl-4-trifluoromethyl-benzoic acid | HCID 59438540 | — |
Reaction Steps
In analogy to the procedure described for the synthesis of example B.10, the title compound was prepared from 2-iodo-4-trifluoromethyl-benzoic acid methyl ester and 2-propyl zinc bromide followed by saponification with sodium hydroxide. MS (m/e): 231.0 (M−H)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09067911B2 |
| Source dataset | uspto-grants-2015_06 |
| ORD ID | ord-df099603302f49aebe17360345609387 |
| Source note | uspto-grants-2015_06 |