HCID 59438388, compound → HCID 59438478, compound

HRID 2177527Notes

Reaction equation

HRID 2177527 reaction equation
[CH3:1][N:2]1[CH:7]([CH3:8])[CH2:6][CH2:5][C:4]([NH2:15])([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:3]1.[CH3:16][O:17][C:18]1[CH:26]=[C:25]([C:27]([F:30])([F:29])[F:28])[CH:24]=[C:23]([S:31][CH3:32])[C:19]=1[C:20](Cl)=[O:21]>>[CH3:1][N:2]1[CH:7]([CH3:8])[CH2:6][CH2:5][C:4]([NH:15][C:20](=[O:21])[C:19]2[C:23]([S:31][CH3:32])=[CH:24][C:25]([C:27]([F:30])([F:28])[F:29])=[CH:26][C:18]=2[O:17][CH3:16])([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:3]1

Participants

3

Reactant 2

HCID 59438388HCID 59438388, compoundHCID 594385012-Methoxy-6-methylsulfanyl-4-trifluoromethyl-benzoyl chloride

Product 1

HCID 59438478HCID 59438478, compound

Procedure

In analogy to the procedure described for the synthesis of example 16, the title compound was prepared from 1,6-Dimethyl-3-phenyl-piperidin-3-ylamine and 2-Methoxy-6-methylsulfanyl-4-trifluoromethyl-benzoyl chloride (Example B.6). MS (m/e): 453.2 (M+H).

Workup

  1. customIn analogy to the procedure described for the synthesis of example 16

Sources & evidence

ORD record
ord-d9dcd780b5a14ba1be3ed55f647d9167
Source dataset
uspto-grants-2015_06
Patent number
US09067911B2

Reaction notes

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