2-Bromo-5-fluoropyridine → 1-phenyl-1H-imidazo[4,5-c]pyridine

HRID 2177547Notes

Reaction equation

HRID 2177547 reaction equation
F[C:2]1[CH:3]=[CH:4][C:5]([N:8]2[C:16]3[CH:15]=[CH:14][N:13]=[CH:12][C:11]=3[N:10]=[CH:9]2)=N[CH:7]=1.Br[C:18]1C=CC(F)=CN=1>>[C:5]1([N:8]2[C:16]3[CH:15]=[CH:14][N:13]=[CH:12][C:11]=3[N:10]=[CH:9]2)[CH:4]=[CH:3][CH:2]=[CH:7][CH:18]=1

Participants

3

Reactant 2

HCID 27831712-Bromo-5-fluoropyridineHCID 904095831-(5-Fluoropyridin-2-yl)-1H-imidazo[4,5-c]pyridine

Product 1

HCID 53284731-phenyl-1H-imidazo[4,5-c]pyridine

Procedure

Intermediate 2 was prepared in a manner analogous to Intermediate 1, substituting 2-bromobenzene for 2-bromo-5-fluoropyridine. MS (ESI): mass calculated for C12H9N3, 197.07; m/z found 198.1 [M+H]+.

Sources & evidence

ORD record
ord-1a14c810f8a24c61856d7dc27af8850d
Source dataset
uspto-grants-2015_06
Patent number
US09066946B2

Reaction notes

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